Treatment with isoniazid preventive therapy does not lead to the development of drug-resistant tuberculosis, South African investigators report in the April 24th edition of AIDS. Drug susceptibility was monitored in gold miners who developed active tuberculosis (TB). Results showed that patients who received isoniazid preventive therapy did not have an increased risk of developing TB which was resistant to the drug. Isoniazid preventive therapy has been shown to halve the risk of developing TB in people with HIV.
http://www.aidsmap.com/en/news/2507DD8E-9DF4-4101-ABF7-E8E701614A9A.asp
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